Top 1,1-Carbonyldiimidazole Manufacturers and Market Trends 2025–2030

Global 1,1-Carbonyldiimidazole market was valued at USD 45.2 million in 2023 and is projected to reach USD 57.8 million by 2030, exhibiting a steady CAGR of 3.7% during the forecast period.
1,1-Carbonyldiimidazole (CDI), a highly versatile and efficient coupling agent in organic synthesis, has transitioned from specialized laboratory use to a vital component in large-scale pharmaceutical and chemical manufacturing processes. Known for its ability to activate carboxylic acids for nucleophilic acyl substitution reactions, CDI stands out due to its mild reaction conditions, high yields, and compatibility with a wide range of functional groups. This makes it indispensable in peptide synthesis, nucleoside analog production, and the creation of complex biomolecules. Compared to traditional reagents like dicyclohexylcarbodiimide, CDI offers superior solubility in organic solvents and generates fewer byproducts, streamlining purification steps and enhancing overall process efficiency in industrial settings.
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